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Biology Class 11 Unit 13: Chromosome and DNA MCQs

228 multiple choice questions with the correct answer for each. Tap an option to check yourself, or switch on "Show all answers". This is page 4 of 5.

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151. Regulation of gene expression is important because it:

Answer: B. allows the cell to express proteins when needed and is the basis of differentiation

152. The mature human body has about how many different cell types?

Answer: C. 200

153. Different cell types differ because of:

Answer: B. differential gene expression

154. In negative control, gene expression is:

Answer: B. turned off by a repressor protein

155. In positive control, gene expression is:

Answer: B. turned on by an activator protein

156. A repressor binds to the:

Answer: B. operator region

157. The lac operon is a classic example of gene regulation in:

Answer: B. bacteria

158. The lac operon consists of a regulatory gene and how many structural genes?

Answer: B. Three (z, y and a)

159. The i gene produces the:

Answer: C. repressor protein

160. The z gene codes for:

Answer: C. beta-galactosidase

161. Beta-galactosidase hydrolyses:

Answer: B. lactose

162. When lactose is absent, the repressor:

Answer: B. binds the operator and prevents transcription of structural genes

163. When lactose is present, the repressor:

Answer: B. is inactivated by the inducer (lactose), so transcription occurs

164. The inducer of the lac operon is:

Answer: B. lactose (allolactose)

165. A mutation is a change in:

Answer: B. the DNA sequence or chromosome structure or number

166. Agents which cause mutations are called:

Answer: B. mutagens

167. The organism in which a mutation occurs is called a:

Answer: B. mutant

168. A physical mutagen is:

Answer: C. UV rays, X-rays and gamma rays

169. A chemical mutagen is:

Answer: C. colchicine, mustard gas and nitrous acid

170. Mutations which occur naturally are called:

Answer: B. spontaneous (natural) mutations

171. Mutations produced artificially are:

Answer: B. induced mutations

172. A change in a single or a few nucleotides is a:

Answer: B. point (gene) mutation

173. A change in the structure or number of chromosomes is:

Answer: B. a chromosomal mutation (aberration)

174. Replacement of one base by another is:

Answer: C. base substitution

175. Addition or removal of one or more nucleotides causes a:

Answer: B. frameshift mutation

176. A frameshift mutation results in:

Answer: B. a completely new codon sequence and a non-functional protein

177. Most mutations are:

Answer: C. harmful

178. Mutations are considered the driving force of:

Answer: B. evolution

179. Harmful mutations are removed from the gene pool by:

Answer: B. natural selection

180. Examples of harmful mutations include:

Answer: B. cancer, microcephaly, Down syndrome and sickle cell anaemia

181. Down syndrome is characterized by:

Answer: B. 2n plus 1 with trisomy 21

182. The total chromosome number in a Down syndrome child is:

Answer: C. 47

183. Down syndrome results from:

Answer: B. non-disjunction of chromosome 21 during maternal meiosis

184. A symptom of Down syndrome is:

Answer: B. a single crease in the palm and a flattened nose

185. Klinefelter's syndrome has the chromosome constitution:

Answer: B. 44 + XXY

186. Klinefelter's patients are:

Answer: B. males with some feminine characters and small testes

187. Klinefelter's syndrome can be treated with:

Answer: B. testosterone at puberty, but it does not help infertility

188. Turner syndrome has the chromosome constitution:

Answer: B. 44 + XO (45 chromosomes)

189. Turner syndrome patients are:

Answer: B. females with short height, webbed neck and infertility

190. Growth hormone and estrogen therapy are used for:

Answer: C. Turner's syndrome

191. Sickle cell anaemia is due to replacement of glutamic acid by:

Answer: B. valine at position 6 of the beta chain

192. Sickle cell anaemia is caused by:

Answer: B. a recessive gene, inherited from both parents

193. Treatment of sickle cell anaemia includes:

Answer: B. blood transfusions, pain relief, fluids, and bone marrow or stem cell transplant

194. Phenylketonuria (PKU) is the inability to break down:

Answer: C. phenylalanine

195. In PKU the defective enzyme is:

Answer: B. phenylalanine hydroxylase

196. PKU is inherited as:

Answer: C. autosomal recessive

197. The treatment of PKU is a diet extremely low in:

Answer: B. phenylalanine

198. The special infant formula for PKU is:

Answer: C. Lofenalac

199. Chromosomes are made of:

Answer: C. DNA and histone proteins

200. The anticodon of a tRNA is:

Answer: B. complementary to the corresponding codon of mRNA

About Biology Class 11 Unit 13 MCQs (Federal Board)

These 228 Biology MCQs cover Class 11 Unit 13: Chromosome and DNA of the Federal Board (FBISE) HSSC-I (1st Year / Class 11) syllabus. They are SLO-based MCQs as per the new pattern for FBISE exams. Each question has four options and the correct answer is shown, so you can practise for the annual examination and find the topics you still need to revise. The questions are split over 5 pages of 50. Use the Print button to save this chapter as a PDF.